Engineering Mechanically Stiff and Elastomeric Nanocomposites by Covalently Crosslinking Poly(glycerol sebacate) and Silicate Nanoplatelets
نویسندگان
چکیده
793 ©2014 Society for Biomaterials
منابع مشابه
Elastomeric and mechanically stiff nanocomposites from poly(glycerol sebacate) and bioactive nanosilicates.
Poly(glycerol sebacate) (PGS) has been proposed for tissue engineering applications owing to its tough elastomeric mechanical properties, biocompatibility and controllable degradation. However, PGS shows limited bioactivity and thus constraining its utilization for musculoskeletal tissue engineering. To address this issue, we developed bioactive, highly elastomeric, and mechanically stiff nanoc...
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Carbon nanotube (CNT)-based nanocomposites often possess properties such as high stiffness, electrical conductivity, and thermal stability and have been studied for various biomedical and biotechnological applications. However, the current design approaches utilize CNTs as physical fillers, and thus, the true potential of CNT-based nanocomposites has not been realized. Here, we introduce a gene...
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Poly(ethylene-g-maleic anhydride) (PEMA)/graphene nanoplatelets (xGn) (PEMA-xGn) composites were prepared by melt dispersion in an internal shear mixer. By adding dicumyl peroxide (DCP), cured poly(ethylene-g-maleic anhydride) C-PEMA was also produced. Different amounts of xGn were introduced into the PEMA in range of 0.5–5 wt. %. The effects of the sequence of feeding additives into the mixer ...
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Biodegradable elastomeric materials are gaining extensive attention in the field of soft tissue engineering. Poly (glycerol sebacate) (PGS) is a novel biocompatible elastomer in this scope. However this polymer has poor mechanical properties especially when the molar ratio of glycerol is higher than sebacic acid. Calcium Titanate (CaTiO3) is a biocompatible ceramic with some degr...
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BACKGROUND Optimal cell sources and scaffold-cell interactions remain unanswered questions for tissue engineering of heart valves. We assessed the effect of different protein precoatings on a single scaffold type (elastomeric poly (glycerol sebacate)) with a single cell source (endothelial progenitor cells). METHODS AND RESULTS Elastomeric poly (glycerol sebacate) scaffolds were precoated wit...
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